In-vitro Antibacterial Study of Crude extract of Barringtonia asiatica (L.) Kurtz Against Salmonella typhi, Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia

^{1, 2}Isaac John Umaru, ¹Fasihuddin Badruddin Ahmed, ³Kerenhappuch Isaac Umaru
¹Faculty of Resource Science and Technology, Universiti Malaysia Sarawak. Malaysia
²Department of Biochemistry, Federal University Wukari, Taraba State. Nigeria
³Department of Biochemistry, University of Maiduguri Borno State, Nigeria
DOI – http://doi.org/10.37502/IJSMR.2022.5213

Abstract

Introduction: The antibiotic-resistant pathogenic bacteria have been recognized as a serious problem for humans and animals. The aims of this study were to evaluate the in-vitro antibacterial study of crude extract of Barringtonia asiatica (L.) Kurtz against Salmonella typhi, Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia. Materials and Methods: Extractions was carried out through conventional method, by soaking the ground, the plant material in non-polar, medium polar and polar solvents in the order of increasing polarity and the crude extracts were tested by the disc diffusion method on nutrient agar medium. Result: The growth inhibition was considered and compared based on the inhibition rate as reported and < 9 mm inhibition is considered inactive in this regards the methanol leaves extract was observed to exhibited higher activity at 500 µg/mL on Klebsiella pneumonia with growth inhibition zone of 16.23 ± 0.06 mm. And lower inhibition was observed for other organism tested at similar concentration. Conclusion: The focus of this study is to provide the prospects of Barringtonia asiatica different solvent from non-polar and polar crude extract as a good agent for combating antibacterial menace and disease resistance from modern medicine.

Keywords: Antibacterial, Crude, extract, Barringtonia asiatica, Salmonella typhi, Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia.

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